High Performance Liquid Chromatography (HPLC-RP) – SIC

SIC

Sophisticated instrumentation center (SIC) was established in September 2011 to expedite the research program at IIT Indore. SIC has now emerged as one of the first such centers in the country providing extensive analytical instrument support to the users of the research fraternity across the country. A major advantage of SIC is its accessibility to the students within the institute as well as to other institutes and industries. A very healthy ratio of students to the time availability on instruments, and quick analysis of external samples makes it a very useful facility.

Make

Thermo Scientific

Model

Vanquish Core

Description

The Vanquish Core HPLC consists of a quaternary pump, autosampler, column oven and PDA detector.

Features

Pump: Quaternary pump with isocratic and gradient solvents composition
Maximum system pressure of 700 bar to utilize smaller particle size columns for higher resolution and faster separations.
Flow range 0-10 mL/min to analyze all kind of samples.
Easy, fast and secure transfer of methods from HPLC to sub-2-micron columns.
pH Range: 0 to 13, chloride concentration upto 0.1 mol/L
Injection volume: 0.01-100 micro-Litre
Sample cooling: 4 to 40 °C
Sample capacity: 216 vials 1.5 ml each
Column compartment thermostatting: 5 to 85 °C
Reversed phase chromatography is equipped with the HPLC.

Submission Form

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Sample requirements

Powder samples: 5 mg

Liquid samples: 2 ml (1 mg/mL concentration)

Applications

Pharmaceutical Applications: To test the quality of drugs, detect impurities, monitor the progress of reactions, qualitative and quantitative analysis, as well as tablet dissolution studies.
Environmental Applications: Analytical control of pollutants, Detection of phenolic compounds in drinking water, Analyzing air pollution, oil spills and plastic pollutants.
Food and Flavor Application: Quality checks of soft drinks and water, Sugar analysis in fruit juices, Preservative analysis, Polycyclic compound analysis, and Separate various ingredients, contaminants, and additives.
Applications in Forensics: Identification and quantification of drugs, Forensic analysis of textile dyes, Determination of drugs in blood, and Analysis of volatile substances.

Handled By Mr. Ghanashyam Bhavsar

ghanashyam@iiti.ac.in